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Description
Mononuclear cells (MNCs) are composed of lymphocytes (T cells, B cells, and NK cells), monocytes, dendritic cells and stem/progenitor cells. These cells are critical components of the immune system and play key roles in the humoral and cell-mediated immune responses. Mononuclear cells are commonly used in research and clinical applications in the areas of immunology, infectious disease, hematological malignancies, vaccine development, transplant therapy, and high-throughput screening.
Bone marrow MNCs are separated from whole bone marrow by a density gradient centrifugation protocol. CD34 depleted mononuclear cells are isolated by removing the CD34+ population from the MNCs using immunomagnetic separation. The CD34 depleted mononuclear cells contain less than 0.1% CD34+ cells. The presence of CD34+ cells is assessed by flow cytometry prior to cryopreservation. The isolated MNCs can be used to isolate subpopulations or used as a control for donor matched CD34+ stem cell experiments (Please request the CD34 depleted flow-through fraction upon ordering CD34+ stem cells).
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
Additional information
| Fill Volume | Min 10 billion TNCs, Min 20 billion TNCs/bag, Custom, 0,75 million/vial, 0.2 million/vial, 0.25 billion TNCs, 0.3 million/vial, 0.5 million/vial, 0.5 billion TNCs, 1 billion TNCs, 1 million/vial, 1.5 million/vial, 2 million/vial, 2.5 billion TNCs, 2.5 million/vial, 4.5mL, 5 million/vial, 5mL, 5 billion TNCs, 10 million/vial, 10mL, 10 billion TNCs, 15 million/vial, 15mL, 20mL, 20 million/vial, 20 billion TNCs/bag, 25mL, 25 million/vial, 30mL, 30 million/vial, 35mL, 40mL, 40 million/vial, 45mL, 50 million/vial, 50mL, 60mL, 70mL, 80-100mL, 80mL, 90mL, 100mL, 100 million/vial, 110mL, 120mL, 130mL, 140mL, 150mL, 150 million/vial, 160mL, 170mL, 180mL, 190mL, 200 million/vial, 200mL, 250mL, 300 million/vial, 450mL, 500mL |
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