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Cord Blood CD34 Depleted Mononuclear Cells, Single Donor, Fresh

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Description

Mononuclear cells (MNCs)are composed of lymphocytes (T cells, B cells, and NK cells), monocytes, dendritic cells, and stem/progenitor cells. These cells are critical components of the immune system and play key roles in the humoral and cell-mediated immune responses. Mononuclear cells are commonly used in research and clinical applications in the areas of immunology, infectious disease, hematological malignancies, vaccine development, transplant therapy, and high-throughput screening.

Mononuclear cells are separated from umbilical cord blood by means of a density gradient centrifugation protocol. Human cord blood CD34 depleted mononuclear cells are isolated from the mononuclear cell fraction by removing the CD34+ population by immunomagnetic separation. The CD34 depleted mononuclear cells contain less than 0.1% CD34+ cells. The presence of CD34+ cells is assessed by flow cytometry prior to cryopreservation. The isolated MNCs can be used to isolate subpopulations or used as a control for donor matched CD34+ stem cell experiments (Please request the CD34 depleted flow-through fraction upon ordering CD34+ stem cells).

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.

Additional information

Anticoagulant

Format

Grade

Species

Cell and Tissue Source

Disease State

Donor Attributes

Product Information Sheet

CB CD34Dep Single – Fresh

Certificate of Analysis

Sample CoA

Material Safety Data Sheet

Cord Blood – Fresh

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