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Cord Blood CD4+CD45RA+ Naïve Helper T Cells, Frozen

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Description

Naïve helper T cells are mature T cells that have left the thymus and have yet to be exposed to an antigen presented on the MHC class II molecule of an antigen-presenting cell (APC). In humans, CD4+ naïve helper T cells are constantly recirculating into the secondary lymphoid tissues in order to optimize the opportunity of finding their specific antigen.

Human cord blood CD4+CD45RA+ naïve helper T cells are enriched by depleting cells expressing CD8, CD14, CD15, CD16, CD19, CD25, CD34, CD36, CD56, CD123, CD45RO, TCRγ/δ, anti-HLA-DR, and CD235a from the mononuclear cell population using immunomagnetic particles leaving purified, untouched CD4+CD45RA+ naïve helper T cells. Isolated cells are characterized by flow cytometry prior to cryopreservation to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.

Additional information

Anticoagulant

Format

Grade

Species

Cell and Tissue Source

Disease State

Donor Attributes

Product Information Sheet

CB CD4CD45RA – Frozen

Certificate of Analysis

Sample CoA

Material Safety Data Sheet

Cord Blood – Frozen

Protocols

Primary Cell Thawing Protocol

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