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Cord Blood CD8+ Cytotoxic T Cells, Fresh

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Description

Human CD8+ cytotoxic T cells, also known as cytotoxic T lymphocytes, defend the body against intracellular pathogens, such as viruses and bacteria, as well as cancerous cells. CD8+ T cells distinguish infected or diseased cells from healthy cells by recognizing antigens presented by MHC class I molecules located on the surface of the inflicted cells. Once the CD8+ T cells recognize a specific antigen it releases cytotoxins that result in apoptosis of the infected or diseased cell.

Human cord blood CD8+ cytotoxic T cells are enriched by depleting cells expressing CD4, CD14, CD15, CD16, CD19, CD34, CD36, CD56, CD61, CD123, TCRγ/δ, and CD235a from the mononuclear cell population using immunomagnetic particles leaving purified, untouched CD8+ cytotoxic T cells. Isolated cells are characterized by flow cytometry to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.

Additional information

Anticoagulant

Format

Grade

Species

Cell and Tissue Source

Disease State

Donor Attributes

Product Information Sheet

CB CD8 – Fresh

Certificate of Analysis

Sample CoA

Material Safety Data Sheet

Cord Blood – Fresh

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